I am interested in using synthetic biology for therapeutic innovation. These days I work on developing methods to rapidly discover novel bioactive microbial metabolites. Molecules of this type play important roles in medicine and they are a key source of antibiotics, anticancer agents or immunosuppressants. I spend most of my time developing sequencing, bioinformatics and molecular biology methods but I also like to think about how we can involve the general public in helping to source new medicines through citizen science projects.
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“Enabling planetary scale survey of the biosynthetic potential of actinobacteria through massively parallel sequencing”
the development of a barcoded PCR protocol, which is designed to directly amplify biosynthetic genes of interest from Actinobacteria without the trouble of DNA isolation methods